2023
[48] Abouzid A., Moustafa A., Allcock N., Najlah M., Elhissi A., Stanley C., Ahmed W., Seville P., Crean S., Forbes R. Elsawy M. Amlexanox-loaded nanoliposomes showing enhanced anti-inflammatory activity in cultured macrophages: A potential formulation for treatment of oral aphthous stomatitis, Journal of Drug Delivery Science and Technology 2023; 79: 104052 DOI: 10.1016/j.jddst.2022.104052
[47] Razavi M., Abdollahi A., Malek-Khatabi A., Ejarestaghi N., Atashi A., Yousefi N., Ebrahimnejad P., Elsawy M., Dinarvand R. Recent advances in PLGA-based nanofibers as anticancer drug delivery systems, Journal of Drug Delivery Science and Technology 2023; 85: 104587 DOI: 10.1016/j.jddst.2023.104587
[46] Bedewya W., Mohamed M., Abdelhameed M., Elsawy M., Al-Muhur M., Ashida N., Abdalla A., Elwaie A., Nagamatsu T., Ali H. Design, synthesis, and antitumor efficacy of novel 5-deazaflavin derivatives backed by kinase screening docking and ADME studies, Journal of Enzyme Inhibition and Medicinal Chemistry 2023; 38: 2220570 DOI: 10.1080/14756366.2023.2220570
[45] Soliman M., Khedr A., Elsawy M. (2023). ‘Chapter 13: Peptide and protein emulsifiers’, in Elsawy M. Peptide Bionanomaterials: From Design to Application. Gewerbestrasse, Switzerland: Springer Nature (ISBN 978-3-031-29359-7) DOI: 10.1007/978-3-031-29360-3_1
[44] Khedr A., Soliman M., Elsawy M. (2023). ‘Chapter 1: Design rules for de novo self-assembling peptide nanostructures’, in Elsawy M. Peptide Bionanomaterials: From Design to Application. Gewerbestrasse, Switzerland: Springer Nature (ISBN 978-3-031-29359-7) DOI: 10.1007/978-3-031-29360-3_1
2022
[43] Elsawy M., Wychowaniec J., Castillo-Díaz L., Smith A., Miller A., Saiani A. Controlling doxorubicin release from peptide hydrogels through fine-tuning drug-peptide fiber interactions, Biomacromolecules 2022; 23: 2624-2634 DOI: 10.102/acs.biomac.2c00356
[42] Elsawy M., Khedr A., Soliman M., Wychowaniec J., Mix & Gel: A new strategy for the development of nanofibrous cell scaffolds through co-assembly of charge complementary binay peptides, oral presentation at 2022 Virtual MRS Meeting & Exhibit
[41] Elsawy M., Khedr A., Soliman M., Wychowaniec J., Mix & Gel: Molecular control of nanomaterial properties through co-assembly of charge complementary binary peptides, oral presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2022, virtual
[40] Khedr A., Soliman M., Elsawy M., “Mix & Gel”: A novel approach for the development of cost-effective multi-component nanofibrillar peptide hydrogels for biomedical applications, poster presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2022, virtual
[39] Soliman M., Khedr A., Elsawy M., Charge effect on the self-assembly and gelation of β-sheet forming ultra-short de novo constrained ionic-complementary peptides, poster presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2022, virtual
2021
[38] Cordeiro A., Patil-Sen Y., Shivkumar M., Patel R., Khedr A., Elsawy M. Nanovaccine Delivery Approaches and Advanced Delivery Systems for the Prevention of Viral Infections: From Development to Clinical Application, Pharmaceutics 2021 ; 13: 2091-2138 DOI: 10.3390/pharmaceutics13122091
[37] Elsawy M., Hayes J., Wychowaniec J., Ultra-short Ionic-complementary Constrained Peptides (UICPs) as a chemical platform for the development of bioinspired multifunctional nanofibrous materials, oral presentation at 2021 Virtual MRS Meeting & Exhibit
2020
[36] Wychowaniec J., Patel R., Leach J., Mathomes R., Chhabria V., Patil-Sen Y., Hidalgo-Bastida A., Forbes R., Hayes J., Elsawy M. Aromatic stacking facilitated self-assembly of ultra-short ionic complementary peptide sequence: β-sheet nanofibres with remarkable gelation and interfacial properties, Biomacromolecules 2020 ; 21: 2670-2680 DOI: 10.1021/acs.biomac.0c00366
[35] Castillo-Díaz L., Ruiz-Pacheco J., Elsawy M., Reyes-Martínez J., Enríquez-Rodríguez A. Self-assembling peptides as an emerging platform for the treatment metabolic syndrome, International Journal of Nanomedicine 2020 ; 15: 10349-10370 DOI: 10.2147/IJN.S278189
[34] Mahmoud S., Samaha D., Mohamed M., Abou Taleb N., Elsawy M., Nagamatsu T., Ali H. Design, synthesis, antitumor activity and molecular docking study of novel 5-deazaalloxazine analogs, Molecules 2020 ; 25: 2518-2544 DOI: 10.3390/molecules25112518
[33] Fischer D., Santorelli S., Elsawy M., Miller A., Marshall K. Efficacy of progestin as local therapy for endometriosis, British Journal of Pharmacology 2020 ; 177: 2535-2536 DOI: 10.1111/bph.15035
[32] Elsawy M. Peptides nanofibres for the fabrication of versatile soft biomaterials, poster presentation at The 11th World Biomaterials Congress WBC Virtual 2020
2019
[31] Reyes-Martínez J., Ruiz-Pacheco J., Flores-Valdéz M., Elsawy M., Vallejo-Cardona A., Castillo-Díaz L. Advanced hydrogels for treatment of diabetes, Journal of Tissue Engineering and Regenerative Medicine 2019 ; 13: 1375-1393 DOI: 10.1002/term.2880
[30] Elsawy M., Patel R., Wychowaniec J., Leach J., Nuttegg C.-M., Hidalgo-Bastida A., Ultra-short constrained β-sheet forming peptides for the fabrication of versatile soft biomaterials, poster presentation at TCES-UKSB joint meeting 2019, Nottingham, UK
[29] Elsawy M. Molecular control of drug release from peptide nanogels, invited talk at Biomaterials for Cell and Drug Delivery Workshop 2019, Manchester, UK
[28] Elsawy M. Ultra-short β-sheet forming peptides: A platform for fabrication of soft biomaterials, invited talk at Lancaster Biomaterials Symposium 2019, Lancaster, UK
[27] Elsawy M., Wychowaniec J., Saiani A., Patel R., Leach J. Ultra-short self-assembling amphiphilic peptides: A versatile platform for soft biomaterials fabrication, oral presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2019, Liverpool, UK
2018
[26] Wychowaniec J., Iliut M., Zhou M., Moffat J., Elsawy M., Pinheiro W., Hoyland J., Miller A., Vijayaraghavan A., Saiani A. Designing peptide / graphene hybrid hydrogels through fine tuning of molecular interactions, Biomacromolecules 2018; 19: 2731-2741 DOI: 10.1021/acs.biomac.8b00333
[25] Burgess K., Workman V., Elsawy M., Miller A., Oceandy D., Saiani A. RNA extraction from self-assembling peptide hydrogels to allow qPCR analysis, PLOS ONE 2018; 13: e0197517 DOI: 10.1371/journal.pone.0197517
[24] Donno R., Elsawy M., Castillo-Díaz L., Pury S., Ashford M., Tirelli N., Miller A., Controlled release of nanoparticles through electrostatic interactions with peptide hydrogels for mRNA delivery, poster presentation at The Ninth European Conference on PAT & QbD Sciences EuPAT9 2018, Manchester, UK (best poster)
[23] Elsawy M., Miller A., Saiani A., Peptide Hydrogels: A Versatile Platform for Drug Delivery, oral presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2018, Bradford, UK
[22] Moinuddin N., Chhabria V., Wychowaniec J., Patil-Sen Y., Forbes R., Saiani A., Elsawy M., Interfacial self-assembly of short peptides into fibrillised microspheres: A potential drug delivery vehicle, poster presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2018, Bradford, UK
2017
[21] Morris O., Elsawy M., Fairclough M., Williams K., McMahon A., Grigg J., Forster D., Miller A., Saiani A., Prenant C., In vivo characterisation of a therapeutically relevant self-assembling 18F- labelled β-sheet forming peptide and its hydrogel using positron emission tomography, Journal of Labelled Compounds and Radiopharmaceuticals 2017; 60: 481-488. DOI: 10.1002/jlcr.3534
[20] Milani A., Fielding L., Greensmith P., Adlam D., Freemont A., Hoyland J., Hodson N., Elsawy M., Miller A., Ratcliffe L., Mykhaylyk O., Armes S., Saunders B., Anisotropic pH-responsive Hydrogels containing Soft or Hard Rod-like Particles Assembled using Low Shear, Chemistry of Materials 2017; 29: 3100-3110 (cover page). DOI: 10.1021/acs.chemmater.7b00110
[19] Gao J., Tang C., Elsawy M., Smith A., Miller A., Saiani A., Controlling self-assembling peptide hydrogel properties through network topology, Biomacromolecules 2017; 18: 826–834. DOI:10.1021/acs.biomac.6b01693
[18] Elsawy M., Castillo-Díaz L., Wychowaniec J., Miller A., Saiani A., Designing self-assembling β-sheet peptide nanofibers for controlling Doxorubicin release kinetics from hydrogels by fine-tuning peptide-drug non-covalent molecular interactions, poster presentation at The Bioinspired Materials Conference 2017, Manchester, UK
2016
[17] Elsawy M., Smith A., Miller A., Saiani A., Modification of hydrophobic face of β-sheet forming peptide: effect on self-assembly and gelation, Langmuir 2016; 32: 4917-4923. DOI: 10.1021/acs.langmuir.5b03841
[16] Castillo-Díaz L., Elsawy M., Saiani A., Gough J., Miller A., Osteogenic differentiation of human mesenchymal stem cells promotes mineralization within a biodegradable peptide-hydrogel, Journal of Tissue Engineering 2016; 7: 1-15. DOI: 10.1177/2041731416649789
[15] Elsawy M., Castillo-Díaz L., Wychowaniec J., Miller A., Saiani A., Tailoring peptide hydrogels for controlling drug release kinetics, oral presentation at Institute of Physics: The Physics of Soft and Biological Matter Conference 2016, Cambridge, UK
[14] Elsawy M., Castillo-Díaz L., Wychowaniec J., Miller A., Saiani A., Controlling Doxorubicin release from β-sheet peptide hydrogels by finely-tuning drug-peptide interactions, oral presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2016, Birmingham, UK
2015
[13] Elsawy M., Martin L., Tikhonova I., Walker B., Smac-derived aza-peptide as an aminopeptidase-resistant XIAP BIR3 antagonist, Protein & Peptide Letters 2015; 22: 836-843. DOI: 10.2174/0929866522666150622101626
[12] Elsawy M., Castillo-Díaz L., Miller A., Saiani A., Stimuli-responsive β-sheet forming peptide hydrogels as drug delivery systems for controlled drug release, oral presentation at Materials Research Society Spring Meeting & Exhibition 2015, San Francisco, California, USA
[11] Elsawy M., Castillo-Díaz L., Miller A., Saiani A., Tailoring drug release kinetics from peptide hydrogels, poster presentation at RAMS Conference 2015, Coventry, UK
[10] Elsawy M., Castillo-Díaz L., Miller A., Saiani A., β-sheet peptide hydrogels as vehicles for drug delivery, poster presentation at Biomaterials Showcase 2015, Manchester, UK
[9] Castillo-Díaz L., Elsawy M., Saiani A., Gough J., Miller A., Osteogenic differentiation of human mesenchymal stem cells within a beta-sheet peptide hydrogel induces mineralisation in vitro, poster presentation at The 9th UK Mesenchymal Stem Cell Meeting 2015, Manchester, UK.
[8] Elsawy M., Miller A., Saiani A., pH-triggered β-hairpin peptide hydrogel formation through intramolecular β-sheet-turn-sheet self-assembly, poster presentation at Royal Society of Chemistry: Biomaterials Chemistry Annual Conference 2015, London, UK
2014
[7] Elsawy M., Smith A., Miller A., Saiani A., Chemically cross-linked peptide-based hydrogels with potential biomedical applications, poster presentation at 26th Annual Conference European Society of Biomaterials 2014, Liverpool, UK
[6] Elsawy M., Smith A., Miller A., Saiani A., Covalently cross-linked peptide-based hydrogels with potential biomedical applications, poster presentation at RAMS Conference 2014, Bath, UK
2013
[5] Elsawy M., Martin L., Tikhonova I., Walker B., Solid phase synthesis of Smac/DIABLO-derived peptides using a “Safety-Catch” resin: identification of potent XIAP BIR3 antagonists, Bioorganic and Medicinal Chemistry 2013; 21: 5004-5011. DOI: 10.1016/j.bmc.2013.06.055
2012
[4] Elsawy M., Hewage C., Walker B., Racemisation of N-Fmoc phenylglycine under mild microwave-SPPS and conventional stepwise SPPS conditions: attempts to develop strategies for overcoming this, Journal of Peptide Science 2012; 18: 302-311. DOI: 10.1002/psc.2398
[3] Elsawy M., Martin L., Walker B., Lactam bridge stabilised Bim peptides promote apoptosis in PC3 prostate cancer cells through Bax activation at a novel trigger site: a promising strategy for cancer therapy, poster presentation at Irish Association for Cancer Research Annual Conference 2012, Belfast, UK
[2] Elsawy M., Martin L., Walker B., Heterogeneous backbone α/β Bim-derived peptide foldamers trigger apoptosis in PC3 prostate cancer cells through Bax activation at a novel activation site, poster presentation at Royal Society of Chemistry 2nd Symposium on Chemical Biology for Drug Discovery 2012, Macclesfield, Manchester, UK
2011
[1] Elsawy M., Martin L., Walker B., Truncation of a 20-mer wild type BIM BH3 domain peptide: identification of the minimum sequence necessary for promoting cell death of prostate cancer (PC3) cells, Biopolymers (Peptide Science) 2011; 96: 472-472, poster presentation at the 22nd American Peptide Symposium, California, San Diego, USA
Invited Talks
[4] Peptides: Bio-inspired Molecular Constructs for the Innovation of Biomedical Nanomaterials. Invited talk at the Faculty of Pharmacy, Cairo University, Cairo, Egypt, 2022 (virtual)
[3] ‘Special Delivery!’ Nanovaccines & Advanced Vaccine Delivery Systems. Invited talk at the AstraZeneca Biopharmaceutical Development Speke STEM Forum, Liverpool, UK, 2022 (virtual)
[2] Peptides: A Platform for Innovation of Biomaterials. Keynote at the Iranian Controlled Release Society Conference, Tehran, Iran, 2022 (virtual)
[1] Peptides: A Platform for the Development of Versatile Bioinspired Biomedical and Pharmaceutical Nanomaterials. Invited talk at the College of Pharmacy, Gulf Medical University, Ajman, UAE, 2021 (virtual)